Wellbutrin SR (Bupropion)

Wellbutrin SR is used for treating depression. It may also be used for other conditions as determined by your doctor.

Wellbutrin SR is an antidepressant. It works in the brain to treat depression. Exactly how it works is not known.

Do not use Wellbutrin SR if:

• you are allergic to any ingredient in Wellbutrin SR;
• you are taking any other medicine that contains bupropion;
• you have a history of an eating disorder (e.g., anorexia, bulimia) or seizures (e.g., epilepsy);
• you are suddenly stopping the use of alcohol or sedatives (e.g., benzodiazepines) after long-term use;
• Contact your doctor or health care provider right away if any of these apply to you.
  
  Some medical conditions may interact with Wellbutrin SR Sustained-Release Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you or a family member has a history of bipolar disorder (manic depression), other mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or substance abuse
  • if you have diabetes, kidney problems, high blood pressure, heart problems (eg, congestive heart failure), or a recent heart attack
  • if you have a history of seizure, head injury, tumor in the brain or spinal cord, or liver problems (eg, cirrhosis)
  
  
  Some MEDICINES MAY INTERACT with Wellbutrin SR Sustained-Release Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
  • Amantadine, antipsychotics (eg, haloperidol, risperidone), corticosteroids (eg, prednisone), insulin, levodopa, MAOIs (eg, phenelzine), nicotine patches, oral hypoglycemics (eg, glipizide), other antidepressants (eg, fluoxetine, amitriptyline), sympathomimetics (eg, pseudoephedrine), theophylline, or tiagabine because they may increase the risk of Wellbutrin SR Sustained-Release Tablets's side effects
  • Carbamazepine, phenobarbital, or phenytoin because they may decrease Wellbutrin SR Sustained-Release Tablets's effectiveness
  • Antiarrhythmics (eg, propafenone, flecainide), beta-blockers (eg, metoprolol), phenothiazines (eg, thioridazine), selective serotonin reuptake inhibitor (SSRI) antidepressants (eg, fluoxetine), or tricyclic antidepressants (eg, nortriptyline) because the risk of their side effects may be increased by Wellbutrin SR Sustained-Release Tablets

Check with your doctor if any of these most common side effects persist or become bothersome:

• constipation; dizziness; headache; indigestion; nausea; tiredness or weakness; vomiting.

• severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); behavior changes (eg, aggression); chest pain; confusion; cough; depression; fainting; hallucinations; irregular heartbeat; mood or mental changes; shortness of breath; swelling of hands or feet; vision disturbances.

Wellbutrin SR is to be used only by the patient for whom it is prescribed. Do not share it with other people.