Glyset (Miglitol)

Glyset is used for treating type 2 diabetes in adults whose diabetes cannot be managed with diet alone. Glyset may be used alone, in combination with other oral diabetes medicines, or with insulin.

Glyset is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose. This decreases blood sugar levels following a meal.

Do not use Glyset if:

• you are allergic to any ingredient in Glyset;
• you have blockage of the stomach or intestine or are at risk for these problems;
• you have long-term (chronic) bowel inflammation, colon ulcers, or stomach or intestine problems that interfere with digestion or nutrient absorption;
• you have diabetic ketoacidosis (high ketone levels) or moderate to severe kidney problems.

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have stomach or intestinal problems, liver problems, or kidney problems

• Insulin or sulfonylureas (eg, glyburide) because side effects may be increased by Glyset
• Digoxin, propranolol, or ranitidine because their effectiveness may be decreased by Glyset

Check with your doctor if any of these most common side effects persist or become bothersome:

• bloating; diarrhea; gas; soft stools; stomach pain.

• severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe stomach pain.

Glyset is to be used only by the patient for whom it is prescribed. Do not share it with other people.

If your symptoms do not improve or if they become worse, check with your doctor.