Prandin (Repaglinide)

Prandin is used for managing type 2 (non-insulin-dependent) diabetes. It is used in addition to diet and exercise to lower blood sugar in adults who cannot manage with diet, exercise, or diabetic medications alone. It may be used with other diabetes medicines.

Prandin is a meglitinide antidiabetic. It works to lower blood glucose (sugar) by stimulating the release of insulin from the pancreas gland. Prandin does not work in type 1 (insulin-dependent) diabetes, because in this condition the pancreas gland is not capable of making or releasing insulin.

Do NOT use Prandin if:

• you are allergic to any ingredient in Prandin
• you have type 1 diabetes (insulin-dependent diabetes) or have elevated ketone levels due to diabetes
• you are also taking gemfibrozil

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription medicine, nonprescription medicine, herbal preparation or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have a history of acidosis, kidney disease, or liver disease

• Rifampin because it may decrease Prandin 's effectiveness
• Beta blockers (eg, propranolol), gemfibrozil, imidazoles (eg, ketoconazole), macrolides and ketolides (eg, erythromycin, azithromycin), monoamine oxidase (MAO) inhibitors (eg, phenelzine), quinolones (eg, ciprofloxacin), or salicylates (eg, aspirin) because the risk of side effects, such as low blood sugar, may be increased
• Insulin because it may increase the risk of Prandin 's side effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Changes in vision; diarrhea; headache; increased heartbeat; increased hunger; joint or back pain; nasal or chest congestion; nervousness; sinus inflammation; sweating; tiredness; tremor.

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain.

If you have any questions about Prandin , please talk with your doctor, pharmacist, or other health care provider.
Prandin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.