Drug Name

Lotrisone (Clotrimazole and Betamethasone)

Drug Uses

Lotrisone is used for treating certain fungal skin infections, including ringworm, athlete's foot, and jock itch. It also relieves redness and itching associated with infection.

Drug Class and Mechanism

Lotrisone is an antifungal and corticosteroid combination. It works by weakening the cell membrane of certain fungi. It also acts as an anti-inflammatory and anti-itching agent.

Warnings/Precautions

Do NOT use Lotrisone Lotion if:

• you are allergic to any ingredient in Lotrisone Lotion
• you are taking pimozide or an ergot alkaloid (eg, ergotamine)

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Lotrisone Lotion. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have diaper rash, eczema, measles, tuberculosis (TB) or a positive TB skin test, chickenpox, shingles, or thinning of the skin
• if you have recently received a vaccination

Some MEDICINES MAY INTERACT with Lotrisone Lotion. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Clarithromycin because the risk of certain side effects may be increased
• Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because they may decrease Lotrisone Lotion's effectiveness
• Ergot alkaloids (eg, ergotamine), imatinib, live vaccines, macrolide immunosuppressants (eg, tacrolimus), pimozide, or ritodrine because their actions and the risk of their side effects may be increased by Lotrisone Lotion
• Hydantoins (eg, phenytoin) or interleukin-2 because their effectiveness may be decreased by Lotrisone Lotion

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lotrisone Lotion may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

• Dry skin; mild burning or stinging at the application site.

Seek medical attention right away if any of these SEVERE side effects occur:

• Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); irritation, redness, blistering, swelling, oozing, or severe burning at the application site; unusual bruising.

More Information

If you have any questions about Lotrisone Lotion, please talk with your doctor, pharmacist, or other health care provider.
Lotrisone Lotion is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.