Simplicef (Cefpodoxime)

Simplicef tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of:

• Staphylococcus intermedius;
• Staphylococcus aureus;
• Streptococcus canis (group G, hemolytic);
• Escherichia coli;
• Pasteurella multocida, and Proteus mirabilis.

Simplicef is an orally administered, extended spectrum, semi-synthetic cephalosporin antibiotic.

• Not for human use. Keep this and all drugs out of reach of children. Antimicrobial drugs, including penicillins and cephalosporins, can cause allergic reactions in sensitized individuals.
• To minimize the possibility of allergic reactions, those handling such antimicrobials, including Simplicef, are advised to avoid direct contact of the product with the skin and mucous membranes.

• Stop giving Simplicef and seek emergency veterinary medical care in the event of an allergic reaction (shortness of breath; hives; swelling of the lips, tongue, or face; rash or fainting), severe nausea, vomiting or diarrhea, mucous or blood in the stool, and unusual bleeding or bruising. Other, less serious side effects such as mild nausea or diarrhea or yeast infection may be more likely to occur.
• Continue to give Simplicef and notify your veterinarian if these symptoms occur.

Before giving Simplicef, tell your veterinarian if your pet is being given another antibiotic (for the same or a different infection), probenecid, a loop diuretic such as furosemide, or warfarin. You may need to have the dosage adjusted. Drugs other than those listed here may also interact with Simplicef. Talk to your veterinarian or pharmacist before giving any prescription or OTC medicines, including vitamins, minerals, and herbal products.